Chitosan
Chitosan: Knowing the History
Chitosan (pronounced Kite-O-San) has long been considered as the "fat magnet". Researches have
it that it is simply a fat inhibitor which appears to work miracles for those in search of a safe way to lose that
body fat.
The chitosan is actually a substance taken from chitin, a polysaccharide found in the
exoskeletons of crustaceans. It is processed by removing the shells from the shellfish like lobster, shrimps and
crabs. How and when chitosan was discovered is the main subject to be tackled here. Let’s consider the following
details.
The origin of chitosan can be traced back to 1811 when "chitin", from which it is derived, was
first discovered by Braconnot, a then professor of the natural history in France. According to some researches,
while Braconnot was conducting research on mushrooms, he isolated what was later to be called chitin.
Some 20 years later, there was a man who authored an article on insects in which he noted that
similar substance was present in the structure of insects as well as the structure of plants. He then called this
amazing substance as "chitin". Basically, the name chitin is derived from Greek, meaning "tunic" or "envelope". The
concept was further known in 1843 when Lassaigne demonstrated the presence of nitrogen in chitin.
After the discovery of chitin, the name "chitosan" emerged in the scene. It was first discovered
by Rouget while experimenting with chitin. Accordingly, Rouget observed that the compound of chitin could be
manipulated through chemical and temperature treatments for it to become soluble. Then, it was in 1878 when
Ledderhose identified chitin to be made of glucosamine and acetic acid. It was not actually until 1894 that
Hoppe-Seyler named the tailored chitin, chitosan.
By the early 20th century, several researches took chitosan as their subject of study. They then
involved sources of chitin, including crab shells and fungai. It was the work of Rammelberg in the 1930s that led
to the confirmation on the identity of chitosan from these sources. It was also noted that by hydrolyzing chitin in
a number of ways, it was determined by experts that chitin is a polysaccharide of glucosamine.
1950s arrived and the use of x-ray analysis had advanced the study of the occurrence of chitin
or chitosan in fungai. However, it is only the most advanced technologies that proved the most reliable in
identifying the presence of chitin as well as cellulose in the cell walls. The first book on chitosan was published
140 years after the initial observation of Braconnot, and that was in 1951.
In the early 1960s, chitosan was investigated for its ability to bind with the red blood cells.
That time also, the substance was considered as a hemostatic agent. Then, for the past three decades, chitosan has
been used at water purification plants for detoxifying water. It is spread over the surface where it absorbs
greases, oils, and other potential toxins.
Today, it is known as a dietary supplement that is good for weight loss. In fact, it has been
marketed for such purpose for about 20 years in Japan as well as in Europe. Many people even call it as the "fat
blocker".
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