Folic Acid Vitamin B12

Folic Acid/Vitamin B12, or cobalamin, is an important vitamin that is soluble in water. Unlike any other water-soluble vitamins, folic acid/vitamin B12 is not excreted quickly in the urine. Rather, it accumulates and is stored in the body, specifically the liver and the kidney. Perhaps as a result of this, deficiency in folic acid/vitamin B12 is not apparent until after 5 or 6 years of consuming a diet that supplies an inadequate amount of this vitamin group.

Folic acid/vitamin B12 acts like a methyl donor and plays an important role in the synthesis of DNA and red blood cells. It has a vital importance in maintaining the health of the myelin, the insulation sheath that surrounds nerve cells. One of the consequences of folic acid/vitamin B12 deficiency is anaemia but it is now clear that it is not the most serious of consequences. The normal blood level of folic acid/vitamin B12 ranges between 200 and 600 picogram/milliliter (148-443 picomol/liter).

Before anaemia is evident, a deficiency in folic acid/vitamin B12 often manifests itself in the development of a neurological dysfunction that is not unlike senile dementia and Alzheimer’s disease. Many patients who are exhibiting symptoms of Alzheimer’s actually suffer from a folic acid/vitamin B12 deficiency. In addition, low levels of this vitamin are linked with asthma, depression, AIDS, multiple sclerosis, tinnitus, diabetic neuropathy, and low sperm counts. Based on this, it is clearly evident that maintaining an adequate amount in the body is crucial.

How much does the body need?

The amount of folic acid/vitamin B12 that our body needs is actually very small. The body needs about 2 micrograms or 2 millionth of a gram each day. However, because folic acid/vitamin B12 is not absorbed very well, we need larger amounts than that. We can do this through increasing folate in your diet or through supplementation. The richest dietary sources of folic acid/vitamin B12 are liver (especially lamb’s liver) and kidneys. You can also get an adequate supply of this vitamin from eggs, cheese, and some species of fish. Contrary to popular belief, vegetables and fruits are actually poor sources.

Supplementation

One of the best ways to maintain adequate levels of folic acid/vitamin B12 in the body is through supplementation. Oral supplementation with this vitamin is safe, efficient, and inexpensive. You can find several drugstores that sell multi-vitamins. Each multi-vitamin pill contains about 100-200 microgram of folic acid/vitamin B12 in cyanocobalamin form. The body will convert this into methylcobalamin or adenosylcobalamin so it can start using it.

How to take it

One of the problems with folic acid/vitamin B12 is its absorption. As stated before, absorption is slow. So even if you take in about 500 micrograms of cyanocobalamin, your body actually only absorbs as little as 1.8 micrograms. This shows that multivitamins do not necessarily provide adequate daily intake.

The best approach in taking folic acid/vitamin B12 is to place a sublingual tablet of methylcobalamin (1000 micrograms) under your tongue and allow it to dissolve. This will actually increase the absorption rate, thereby allowing the body to maintain adequate amounts.

Recommended Dosage for Folic Acid/Vitamin B12 Deficiency

In cases of deficiency, 1000 micrograms per day might not be enough. The recommended dosage is 2000 micrograms per day for one month. After the first month, the 1000 microgram/day may be followed.